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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Brian LaFever | 351 | 2003-2018 | |
| 2 | Pat Howe | 316 | 2005-2019 | |
| 3 | David Perdomo | 291 | 2000-2012 | |
| 4 | Adam Nance | 286 | 2008-2020 | |
| 5 | Jason Brown | 279 | 2007-2021 | |
| 6 | Luis Soto | 275 | 2005-2017 | |
| 7 | Rogelio Sanchez | 239 | 2001-2016 | |
| 8 | Dan Walker | 225 | 2001-2015 | |
| 9 | C.J. Sidney | 219 | 2000-2010 | |
| 10 | Andrew DeGroff | 217 | 2000-2010 | |
| 11 | Willie Granados | 215 | 2000-2010 | |
| 12 | Andre Cunningham | 194 | 2008-2019 | |
| 13 | Kevin Iskra | 192 | 2010-2019 | |
| 14 | Rodolfo Alvarez | 187 | 2000-2008 | |
| 15 | J.R. Pohlman | 184 | 2000-2008 | |
| 16 | Clark Owens# | 182 | 2018-2023 | |
| 17 | Joel Harrison | 169 | 2001-2017 | |
| 18 | Chris Beasley# | 164 | 2016-2023 | |
| 19 | Johnny Ortega* | 162 | 2000-2016 | |
| 19 | Jeremy Yamakawa | 162 | 2005-2020 | |
| 21 | Danny Cruz | 156 | 2000-2011 | |
| 22 | Jon Pitts# | 143 | 2014-2023 | |
| 23 | Mitch Philipp | 142 | 2013-2020 | |
| 24 | Aharon Kroyan# | 136 | 2019-2023 | |
| 25 | Jim Mireles | 120 | 2007-2015 | |
| 26 | Bobby Mendoza# | 118 | 2018-2022 | |
| 27 | Joham Fafes | 111 | 2004-2014 | |
| 28 | Derek Maher# | 110 | 2019-2023 | |
| 29 | Julio Ramirez | 105 | 2003-2014 | |
| 29 | Mike Thompson# | 105 | 2014-2023 | |
| 31 | Danny Pierce# | 98 | 2021-2023 | |
| 31 | Steve Wooldridge# | 98 | 2018-2022 | |
| 33 | Josh Miller | 95 | 2000-2013 | |
| 34 | Jon Atwell | 92 | 2009-2019 | |
| 34 | Mitchell Young | 92 | 2000-2007 | |
| 36 | Sean Drummond | 90 | 2000-2007 | |
| 36 | Ernesto Ramirez# | 90 | 2017-2023 | |
| 38 | Eric Bradstreet# | 88 | 2016-2022 | |
| 38 | Luis Pompa | 88 | 2012-2019 | |
| 40 | Brian Shultz# | 87 | 2018-2023 | |
| 41 | Dan Brewer# | 86 | 2018-2023 | |
| 41 | Danny Solis | 86 | 2008-2019 | |
| 43 | Tsunemi Higaki | 84 | 2007-2016 | |
| 44 | Caleb Strouse | 83 | 2000-2014 | |
| 45 | George Dashiell | 82 | 2000-2009 | |
| 46 | Jeremy Moore# | 81 | 2014-2023 | |
| 47 | Russ Bansemer | 80 | 2010-2019 | |
| 48 | Matt Lawson# | 77 | 2017-2022 | |
| 49 | Matt O'Brien | 75 | 2000-2006 | |
| 50 | Juan Lopez | 71 | 2012-2018 | |
| 51 | Josh Terrien# | 68 | 2017-2022 | |
| 52 | Ian McKibbins# | 67 | 2019-2022 | |
| 53 | David Dutton | 66 | 2004-2015 | |
| 54 | Miles Hayes | 64 | 2000-2012 | |
| 55 | Jonathan Ashley# | 63 | 2004-2021 | |
| 55 | Ben Callahan# | 63 | 2020-2023 | |
| 55 | Tony Ochoa# | 63 | 2012-2023 | |
| 58 | Eric Hayes# | 62 | 2022-2023 | |
| 59 | Jay Thibodeaux# | 61 | 2014-2023 | |
| 60 | Keith Brosch# | 59 | 2021-2023 | |
| 61 | Jim Anderson# | 58 | 2021-2023 | |
| 61 | David Atchley | 58 | 2008-2016 | |
| 61 | Chao-yang Shui | 58 | 2002-2008 | |
| 64 | Alfonso Alvarez | 57 | 2013-2019 | |
| 64 | Vince Austin | 57 | 2015-2019 | |
| 64 | Chris Cocks | 57 | 2005-2011 | |
| 67 | Justin LaMontagne | 55 | 2014-2016 | |
| 67 | Gabriel Perez | 55 | 2006-2018 | |
| 67 | Tom Tillotson | 55 | 2007-2016 | |
| 67 | Billy Totten# | 55 | 2021-2023 | |
| 71 | Tadao Kitagawa | 54 | 2001-2010 | |
| 71 | David Maynard | 54 | 2006-2013 | |
| 73 | Joe Engle | 53 | 2012-2018 | |
| 74 | Jose Duarte# | 50 | 2018-2021 | |
| 75 | John Jones | 48 | 2000-2003 | |
| 76 | Dustin Houston | 47 | 2006-2016 | |
| 76 | Josh Spencer# | 47 | 2016-2023 | |
| 78 | Jonathan Rivera | 46 | 2010-2018 | |
| 79 | A.J. Cook# | 45 | 2020-2023 | |
| 80 | Mike Melin# | 44 | 2015-2020 | |
| 81 | Emilio Abreu# | 43 | 2012-2023 | |
| 81 | Tim Schellin# | 43 | 2021-2023 | |
| 83 | Jason Armstrong | 42 | 2009-2018 | |
| 83 | German Galvan | 42 | 2014-2017 | |
| 83 | Jerry Robinson# | 42 | 2023-2023 | |
| 86 | Matt Liebler | 41 | 2015-2020 | |
| 86 | Nelson Ziersch# | 41 | 2022-2023 | |
| 88 | Ramon Hernandez | 40 | 2002-2014 | |
| 88 | Gus Marquez# | 40 | 2019-2023 | |
| 90 | Steve Ausman | 39 | 2008-2019 | |
| 90 | Jimmy MacDonald# | 39 | 2017-2021 | |
| 90 | Vance West | 39 | 2010-2017 | |
| 93 | Justin Bellamy# | 37 | 2020-2023 | |
| 93 | Quincy Cook | 37 | 2012-2020 | |
| 93 | Mike Green# | 37 | 2020-2023 | |
| 93 | Enrique Islas | 37 | 2013-2020 | |
| 93 | Jon Wagner# | 37 | 2019-2023 | |
| 98 | John Piscitelli# | 36 | 2022-2023 | |
| 99 | Adam Staley | 35 | 2000-2008 | |
| 100 | Jason Coppa# | 34 | 2021-2023 |
