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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Omar Pena | 378 | 2000-2011 | |
| 2 | Paul Pittman# | 350 | 2013-2023 | |
| 3 | Zach Swint | 304 | 2001-2016 | |
| 4 | Ken Bennett | 222 | 2000-2009 | |
| 5 | Bobby Tapia# | 211 | 2008-2023 | |
| 6 | Austin Compton# | 208 | 2015-2023 | |
| 7 | Luis Vasquez | 202 | 2006-2016 | |
| 8 | Mike Plocher | 199 | 2000-2009 | |
| 9 | Carlos Martinez | 189 | 2003-2016 | |
| 10 | Matthew Little# | 184 | 2018-2023 | |
| 11 | Alberto Ojeda* | 176 | 2002-2016 | |
| 12 | Gong-sun Thum | 164 | 2011-2020 | |
| 13 | Bob Johnson | 159 | 2000-2012 | |
| 14 | Juan Membreno | 157 | 2006-2020 | |
| 15 | Ryan Forsythe# | 156 | 2018-2023 | |
| 16 | Julio Rojo | 153 | 2000-2008 | |
| 17 | Rocky Hawke# | 140 | 2018-2023 | |
| 18 | Fernando Serrano | 120 | 2010-2020 | |
| 19 | Roberto Gonzalez | 119 | 2000-2003 | |
| 20 | Ivan Galvan | 115 | 2010-2019 | |
| 21 | Chris Stover | 111 | 2016-2020 | |
| 22 | Tae-hyeon Hahn | 110 | 2009-2017 | |
| 23 | Travis Collier# | 104 | 2010-2022 | |
| 24 | Danny Greeman | 103 | 2004-2010 | |
| 25 | Steve Fisher | 99 | 2010-2018 | |
| 26 | Ton Ariëns# | 98 | 2021-2023 | |
| 26 | Lorenzo Novo | 98 | 2000-2013 | |
| 26 | Kevin Tibbens | 98 | 2000-2015 | |
| 29 | Marco Fermin | 97 | 2000-2008 | |
| 30 | Jason Saunders# | 95 | 2018-2023 | |
| 31 | Jason Morrow | 91 | 2001-2010 | |
| 32 | Dan James# | 84 | 2015-2020 | |
| 32 | Josh Law# | 84 | 2017-2023 | |
| 34 | Willie Arellanes | 83 | 2000-2009 | |
| 34 | Xavier Jackson | 83 | 2004-2011 | |
| 36 | Eric Brewer# | 82 | 2015-2023 | |
| 36 | Manny Perez | 82 | 2000-2006 | |
| 38 | Dan Taylor | 81 | 2004-2017 | |
| 39 | Nick Seago# | 73 | 2018-2023 | |
| 40 | Jose Torres | 68 | 2000-2006 | |
| 41 | Miguel Meza | 64 | 2009-2020 | |
| 41 | Bobby Oliver# | 64 | 2019-2021 | |
| 43 | Carlos Martinez | 62 | 2008-2015 | |
| 44 | Jeremy Alfano# | 61 | 2020-2022 | |
| 45 | Jody Garner | 60 | 2001-2012 | |
| 45 | Cipta Lubis | 60 | 2007-2012 | |
| 45 | Elijah Moody# | 60 | 2021-2022 | |
| 48 | Nate Bacle# | 59 | 2015-2021 | |
| 48 | Charlie Waters | 59 | 2001-2012 | |
| 50 | Paul McCarthy# | 58 | 2018-2023 | |
| 51 | Mike Townsend# | 57 | 2018-2023 | |
| 52 | Dane Howell | 55 | 2002-2012 | |
| 52 | Isaiah Stanley | 55 | 2001-2012 | |
| 54 | Walt Lepore | 54 | 2014-2020 | |
| 54 | Stephen Stewart | 54 | 2000-2007 | |
| 56 | Brian Roseman# | 53 | 2023-2023 | |
| 57 | Dave Jones | 52 | 2017-2022 | |
| 58 | T.J. Donovan# | 51 | 2020-2023 | |
| 59 | Heath Sherlock# | 50 | 2021-2023 | |
| 60 | Norman Moyers | 49 | 2000-2007 | |
| 61 | Travis LeBrun | 48 | 2011-2016 | |
| 62 | George Dashiell | 47 | 2000-2009 | |
| 62 | Victor Mendez# | 47 | 2021-2023 | |
| 64 | Brian Byrd# | 43 | 2014-2023 | |
| 64 | Chris Denney# | 43 | 2018-2021 | |
| 64 | Kyle Fitzpatrick | 43 | 2009-2015 | |
| 64 | Dan Powell | 43 | 2004-2012 | |
| 68 | Ricky Ordonez# | 41 | 2017-2023 | |
| 69 | Jose Lazaro# | 39 | 2022-2023 | |
| 69 | Severo Salcido# | 39 | 2013-2023 | |
| 71 | Phil Cook | 38 | 2006-2017 | |
| 71 | Danny Morales | 38 | 2010-2015 | |
| 71 | Chris Pargeon | 38 | 2006-2015 | |
| 74 | Steve Pate | 37 | 2000-2009 | |
| 75 | Keagan Deming# | 36 | 2019-2022 | |
| 75 | Gary Draeger# | 36 | 2016-2023 | |
| 75 | Jim Johnston | 36 | 2006-2013 | |
| 78 | Pat Albury | 35 | 2014-2016 | |
| 78 | Tony Arteaga# | 35 | 2016-2021 | |
| 80 | Bert Vega | 34 | 2000-2001 | |
| 81 | Jasper Sloan | 33 | 2002-2011 | |
| 82 | Tiberio Donelli | 32 | 2001-2011 | |
| 83 | Travis Baynes | 31 | 2000-2005 | |
| 83 | Jonathan Cunningham# | 31 | 2021-2023 | |
| 83 | Jake Densberger# | 31 | 2017-2022 | |
| 83 | Steve Post# | 31 | 2022-2023 | |
| 87 | Eric Hicks# | 30 | 2022-2023 | |
| 88 | Chris Goldsmith# | 29 | 2022-2023 | |
| 88 | Alex Natera# | 29 | 2021-2023 | |
| 90 | Juan Garcia# | 28 | 2010-2023 | |
| 90 | Roberto Perez# | 28 | 2017-2023 | |
| 90 | Hua Pian | 28 | 2000-2003 | |
| 93 | Ryan Young | 27 | 2011-2017 | |
| 94 | Brock Farlow# | 26 | 2017-2019 | |
| 94 | Josh Tschinkel | 26 | 2003-2010 | |
| 96 | John Gadsden# | 25 | 2022-2023 | |
| 96 | Jaden Gregory | 25 | 2007-2017 | |
| 96 | Earl Lindsey | 25 | 2007-2013 | |
| 96 | Kevin Schneider# | 25 | 2023-2023 | |
| 100 | Robbie Charles | 24 | 2000-2002 |
